Of Netherlandish origin but born in Padua, Italy, Sustris trained with his father, Lambert, a painter in Titian’s circle. He worked briefly in Rome and went on to spent four years in the painter Giorgio Vasari’s studio in Florence. His first decorative project was in the Fugger Palace (1568–1573) for a powerful banking family in Augsburg, Germany. 

One of the very few studies that can be directly connected to that project, the drawing depicts Euterpe, the muse of music, holding a lyre and organ pipes. Sustris combined Italianate iconography with a technique reminiscent of Vasari and an extreme refinement of form found in works by Parmigianino. This drawing provides evidence of the original appearance and rare beauty of the fresco cycle, which was badly damaged in World War II.